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Cardiovascular HealthBrain HealthGeneral WellnessWomen’s Health

EstroFactors®

Metagenics

Last updated: Oct 04, 2025

EstroFactors® is a science-based supplement that provides a blend of phytonutrients designed to harmonize women’s estrogen metabolism and features HMR lignans to reduce aromatase activity.*

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ingredients

Ingredients*

We only evaluate bioactive ingredients—the ones that truly contribute to a product's performance. Below is a list of bioactive ingredients found in this product.

For each ingredient, the quantity in parentheses indicates the amount per serving.

Vitamin A is a fat-soluble nutrient essential for vision, growth, immune function, and overall health.

(as d-alpha tocopheryl succinate and d-alpha tocopheryl polyethylene glycol 1000 succinate††). Vitamin E is a fat-soluble nutrient essential for immune function and skin health.

Riboflavin or Vitamin B2 is for essential for growth and the production of red blood cells.

Vitamin B6 is a water-soluble nutrient essential for brain development, function, and promoting the body's metabolism.

Folate is a type of B vitamin that is key for cell growth and metabolism, often found in leafy green vegetables, beans, peas, and fortified foods.

Vitamin B12 is a water-soluble vitamin essential for brain function and the production of red blood cells in the body.

Rice protein matrix and polyphenols from hops are plant-based nutrients that provide protein for muscle and tissue support along with antioxidant compounds that help protect cells and reduce inflammation.

Diindolylmethane (DIM) complex is a compound found in cruciferous vegetables that supports healthy estrogen metabolism and may promote hormone balance.

Leaf Extract [standardized to 60% (60 mg) catechins and 40% (40 mg) epigallocatechin gallate (EGCG)] Decaffeinated green tea leaf extract is a concentrated source of antioxidants, particularly catechins like EGCG, that support metabolism, heart health, and cellular protection without the stimulating effects of caffeine.

7-Hydroxymatairesinol (HMR) potassium acetate complex is a plant lignan compound that the body can convert into enterolactone, which may support hormonal balance, antioxidant activity, and overall cellular health.

N-Acetyl-L-Cysteine is a supplemental form of the amino acid cysteine that supports antioxidant production, particularly glutathione, and helps protect the liver, lungs, and other tissues from oxidative stress.

Metagenics Proprietary Mix of Curcumin [from Curcuma longa L. rhizome extract standardized to 40% (20 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum- graecum seed extract)

Fenugreek galactomannans are a type of water-soluble fiber extracted from fenugreek seeds. They are used in supplements for their potential to support healthy blood sugar and cholesterol levels, as well as for their prebiotic properties that aid gut health.

Curcumin is an active, anti-inflammatory compound found in the turmeric, known for its vibrant yellow color and numerous health benefits.

Mixed carotenoids (including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein) are a blend of plant pigments that act as antioxidants, supporting eye health, skin protection, and immune function.

*These product and ingredient description statements have not been evaluated by the Food and Drug Administration (FDA). This product or its ingredients are not intended to diagnose, treat, cure or prevent any disease.

Product description and ingredient list are obtained from the product's brand/company website. Ingredient description is provided by our expert.

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