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Glucosamine Chondroitin Complex with MSM Triple Strength + Vitamin D3

WhatToTrustTM Score
12345678910

NatureMade®

Last updated: Feb 18, 2026

Nature Made® Glucosamine Chondroitin with MSM (popularly known as Triple Flex®) plus D3 is a joint and muscle support formula.

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ingredients

Ingredients*

We only evaluate bioactive ingredients—the ones that truly contribute to a product's performance. Below is a list of bioactive ingredients found in this product.

For each ingredient, the quantity in parentheses indicates the amount per serving.

Vitamin D3 is a form of vitamin D that the body produces in response to sun exposure, essential for bone health and immune system function.

Sodium is a mineral essential for maintaining fluid balance and nerve function in the human body.

Glucosamine hydrochloride is a form of glucosamine, a naturally occurring compound found in cartilage, commonly used to support joint health and alleviate symptoms of osteoarthritis.

Chondroitin sulfate sodium is a compound naturally found in cartilage that is commonly used as a supplement to support joint health and reduce the symptoms of osteoarthritis.

Methylsulfonylmethane (MSM) is an organic sulfur compound commonly used to support joint health, reduce inflammation, and alleviate pain associated with osteoarthritis and muscle soreness.

*These product and ingredient description statements have not been evaluated by the Food and Drug Administration (FDA). This product or its ingredients are not intended to diagnose, treat, cure or prevent any disease.

Product description and ingredient list are obtained from the product's brand/company website. Ingredient description is provided by our expert.

WhatToTrustTM scores are based on ingredient quality tests as well as pre-clinical and clinical testing to ensure that a product is scientifically developed and manufactured.

Breakdown of WhatToTrustTM Score for this product

WhatToTrustTM Science Score

5/10

Ingredient Quality Testing (Batch-to-Batch Testing)

Identity and Potency Testing
yes
Purity/Contaminant Testing
yes

Ingredient Validation Testing

Ingredient Validation Pre-clinical Testing (non-Canomiks test)
no
CanTrust by Canomiks® Ingredient Validation Pre-clinical Testing and Certification
no
Ingredient Clinical Trial/Testing
yes - (Product website does not mention clinical trial, but similar ingredients have been clinically tested.)
Borrowed Science
no

Product Validation Testing

Product Validation Pre-clinical Testing (non-Canomiks test)
no
CanTrust by Canomiks® Product Validation Pre-clinical Testing and Certification
no
Product Clinical Trial/Testing
no
Borrowed Science
no
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